Gene Freq TP53 42 PIK3CA 17.8 PTEN 9.7 APC 7.3 VHL 6.9 KRAS 6.7 MLL3 6.6 MLL2 5.9 ARID1A 5.4 PBRM1 5.4 NAV3 4.6 EGFR 4.6 NF1 4.4 PIK3R1 4.4 CDKN2A 3.6 GATA3 3.2 RB1 3.2 NOTCH1 3.1 FBXW7 3 CTNNB1 2.9 DNMT3A 2.8 MAP3K1 2.7 FLT3 2.7 MALAT1 2.7 TSHZ3 2.6 KEAP1 2.6 CDH1 2.5 ARHGAP35 2.5 CTCF 2.4 NFE2L2 2.3 SETBP1 2.2 BAP1 2 NPM1 1.8 RUNX1 1.6 NRAS 1.5 IDH1 1.5 TBX3 1.4 MAP2K4 1.4 RPL22 1 STK11 0.9 CRIPAK 0.7 CEBPA 0.5 KDM6A 2 EPHA3 2.1 AKT1 0.9 STAG2 2.2 BRAF 1.5 AR 1.2 AJUBA 0.8 EPPK1 1.4 TSHZ2 1.8 PIK3CG 1.7 SOX9 0.7 ATM 3.3 CDKN1B 0.7 WT1 1 HGF 1.7 KDM5C 2 PRX 0.9 ERBB4 2.1 MTOR 3 TLR4 1.9 U2AF1 0.8 ARID5B 1.6 TET2 1.6 ATRX 2.8 MLL4 2 ELF3 0.6 BRCA1 1.9 LRRK2 2.8 POLQ 2.4 FOXA1 0.8 IDH2 0.8 CHEK2 0.9 KIT 1.4 HIST1H1C 0.6 SETD2 3.6 PDGFRA 1.9 EP300 2.5 FGFR2 1.5 CCND1 0.6 EPHB6 1.6 SMAD4 1.4 FOXA2 0.5 USP9X 2.1 BRCA2 2.7 NFE2L3 0.8 FGFR3 1 ASXL1 1.3 TGFBR2 1.1 SOX17 0.3 CDKN1A 0.6 B4GALT3 0.2 SF3B1 1.3 TAF1 2.3 PPP2R1A 1.5 CBFB 0.7 ATR 2.4 SIN3A 1.1 VEZF1 0.6 HIST1H2BD 0.4 EIF4A2 0.8 CDK12 1.5 PHF6 0.8 SMC1A 1.5 PTPN11 1 ACVR1B 1 MAPK8IP1 0.7 H3F3C 0.4 NSD1 2.4 TBL1XR1 0.8 EGR3 0.3 ACVR2A 0.6 MECOM 1.5 LIFR 1.2 SMC3 1.2 NCOR1 2.2 RPL5 0.7 SMAD2 0.9 SPOP 0.7 AXIN2 0.9 MIR142 0.2 RAD21 0.9 ERCC2 0.7 CDKN2C 0.2 EZH2 0.8 PCBP1 0.3