GO.ID Description p.Val FDR Phenotype Genes GO:0044782 cilium organization 4.84560401904726e-16 4.84560401904726e-16 +1 CCDC39,CFAP126,RSPH1,CCDC65,DYNLRB2,TEKT1,RSPH4A,CFAP52,CFAP73,SPEF1,FOXJ1,ZMYND10,DNAH7,PIFO,CFAP54,DRC1,CFAP53,CFAP221,NME5,CEP126,LRRC6,TMEM231,IQUB,SPAG1,MNS1,RFX4,TMEM67,IQCG,NPHP1,CETN2,IFT46,DNAAF4,TCTEX1D2,WDR92,SPAG16,IFT22,CFAP298,TCTN1 GO:0003341 cilium movement 4.84560401904726e-16 4.84560401904726e-16 +1 ROPN1L,CCDC39,CCDC65,TEKT1,RSPH4A,CFAP73,ZBBX,SPEF1,ZMYND10,DNAH11,DNAH7,CFAP54,DNAH9,DRC1,CFAP53,CFAP221,SPA17,NME5,LRRC6,MNS1,IQCG,DNAAF4,SPAG16,CFAP298 GO:0060271 cilium assembly 2.9612405907802705e-15 2.9612405907802705e-15 +1 CCDC39,RSPH1,CCDC65,DYNLRB2,TEKT1,RSPH4A,CFAP52,CFAP73,SPEF1,FOXJ1,ZMYND10,DNAH7,CFAP54,DRC1,CFAP53,CFAP221,NME5,CEP126,LRRC6,TMEM231,IQUB,SPAG1,MNS1,RFX4,TMEM67,IQCG,NPHP1,CETN2,IFT46,DNAAF4,TCTEX1D2,WDR92,SPAG16,IFT22,CFAP298,TCTN1 GO:0035082 axoneme assembly 1.7968022578780345e-13 1.7968022578780345e-13 +1 CCDC39,RSPH1,CCDC65,RSPH4A,CFAP73,SPEF1,FOXJ1,ZMYND10,DNAH7,DRC1,LRRC6,SPAG1,MNS1,IQCG,DNAAF4,WDR92,SPAG16 GO:0007018 microtubule-based movement 7.710319162271905e-13 7.710319162271905e-13 +1 ROPN1L,CCDC39,CCDC65,DYNLRB2,TEKT1,RSPH4A,CFAP73,ZBBX,SPEF1,ZMYND10,DNAH11,DNAH7,CFAP54,DNAH9,DRC1,CFAP53,CFAP221,SPA17,DNAH6,NME5,LRRC6,MNS1,KIF9,IQCG,IFT46,DNAAF4,TCTEX1D2,SPAG16,IFT22,CFAP298,UCHL1 GO:0001578 microtubule bundle formation 5.296480682576643e-12 5.296480682576643e-12 +1 CCDC39,RSPH1,CCDC65,RSPH4A,CFAP73,SPEF1,FOXJ1,ZMYND10,DNAH7,DRC1,LRRC6,SPAG1,TPPP3,MNS1,IQCG,DNAAF4,WDR92,SPAG16 GO:0070286 axonemal dynein complex assembly 4.371787469335731e-9 4.371787469335731e-9 +1 CCDC39,CCDC65,CFAP73,ZMYND10,DNAH7,DRC1,LRRC6,SPAG1,DNAAF4,WDR92 GO:0060285 cilium-dependent cell motility 8.73520551105975e-9 8.73520551105975e-9 +1 ROPN1L,CCDC39,CCDC65,TEKT1,RSPH4A,DNAH11,DNAH7,CFAP54,DRC1,DNAH6,LRRC6,MNS1,EFHC1,IQCG,SPAG16 GO:0001539 cilium or flagellum-dependent cell motility 8.73520551105975e-9 8.73520551105975e-9 +1 ROPN1L,CCDC39,CCDC65,TEKT1,RSPH4A,DNAH11,DNAH7,CFAP54,DRC1,DNAH6,LRRC6,MNS1,EFHC1,IQCG,SPAG16 GO:0003351 epithelial cilium movement involved in extracellular fluid movement 1.1099844642799555e-7 1.1099844642799555e-7 +1 ROPN1L,CCDC39,DNAH11,CFAP53,SPA17,NME5,LRRC6,DNAAF4,SPAG16 GO:0006858 extracellular transport 2.694504723399049e-7 2.694504723399049e-7 +1 ROPN1L,CCDC39,DNAH11,CFAP53,SPA17,NME5,LRRC6,DNAAF4,SPAG16 GO:0007389 pattern specification process 0.0000032613971044865127 0.0000032613971044865127 +1 CCDC39,IRX3,FOXJ1,C9ORF116,DNAH11,PIFO,DRC1,CFAP53,FOLR1,LRRC6,MNS1,RFX4,HEY1,PAX6,HES1,DNAAF4,CRB2,NDRG4,MSX1,APC2,WLS,SMAD1,TCTN1 GO:0036159 inner dynein arm assembly 0.000003616483836917849 0.000003616483836917849 +1 CCDC39,CFAP73,ZMYND10,DNAH7,LRRC6,DNAAF4 GO:0044458 motile cilium assembly 0.000037049119212140204 0.000037049119212140204 +1 CCDC39,FOXJ1,ZMYND10,CFAP221,LRRC6,MNS1,IQCG,SPAG16 GO:0060294 cilium movement involved in cell motility 0.00015684550400493213 0.00015684550400493213 +1 ROPN1L,CCDC39,TEKT1,RSPH4A,DNAH11,CFAP54,LRRC6,MNS1,IQCG,SPAG16 GO:0099111 microtubule-based transport 0.0002250895745752648 0.0002250895745752648 +1 ROPN1L,CCDC39,DYNLRB2,DNAH11,CFAP53,SPA17,NME5,LRRC6,IFT46,DNAAF4,TCTEX1D2,SPAG16,IFT22,UCHL1 GO:0007283 spermatogenesis 0.0006318405018193599 0.0006318405018193599 +1 ROPN1L,RSPH1,PGAM2,FOXJ1,C9ORF24,CFAP54,SPAG8,SPA17,TSNAXIP1,PACRG,GJA1,NME5,ADCYAP1R1,MNS1,MORN2,IQCG,NPHP1,CETN2,SPAG16,SOX9 GO:0007368 determination of left/right symmetry 0.0007688080755063532 0.0007688080755063532 +1 CCDC39,FOXJ1,C9ORF116,DNAH11,DRC1,CFAP53,FOLR1,LRRC6,DNAAF4,NDRG4 GO:0048232 male gamete generation 0.0009396128752804234 0.0009396128752804234 +1 ROPN1L,RSPH1,PGAM2,FOXJ1,C9ORF24,CFAP54,SPAG8,SPA17,TSNAXIP1,PACRG,GJA1,NME5,ADCYAP1R1,MNS1,MORN2,IQCG,NPHP1,CETN2,SPAG16,SOX9 GO:0009855 determination of bilateral symmetry 0.0011822757145697406 0.0011822757145697406 +1 CCDC39,FOXJ1,C9ORF116,DNAH11,DRC1,CFAP53,FOLR1,LRRC6,DNAAF4,NDRG4 GO:0009799 specification of symmetry 0.0012331256101485012 0.0012331256101485012 +1 CCDC39,FOXJ1,C9ORF116,DNAH11,DRC1,CFAP53,FOLR1,LRRC6,DNAAF4,NDRG4 GO:0060287 epithelial cilium movement involved in determination of left/right asymmetry 0.0012331256101485012 0.0012331256101485012 +1 CCDC39,DNAH11,CFAP53,LRRC6 GO:0097722 sperm motility 0.0026342673016151123 0.0026342673016151123 +1 ROPN1L,CCDC39,TEKT1,DNAH11,LRRC6,MNS1,IQCG,SPAG16 GO:0030317 flagellated sperm motility 0.0026342673016151123 0.0026342673016151123 +1 ROPN1L,CCDC39,TEKT1,DNAH11,LRRC6,MNS1,IQCG,SPAG16 GO:0003352 regulation of cilium movement 0.0026342673016151123 0.0026342673016151123 +1 CCDC39,CCDC65,DNAH11,DRC1,CFAP298 GO:0060632 regulation of microtubule-based movement 0.0027858913021159043 0.0027858913021159043 +1 CCDC39,CCDC65,DNAH11,DRC1,TCTEX1D2,CFAP298 GO:0071773 cellular response to BMP stimulus 0.006497318303121793 0.006497318303121793 +1 FSTL1,SFRP4,HES1,TGFB2,CRB2,MSX1,CERS1,RGMA,SMAD1,SOX9 GO:0071772 response to BMP 0.006497318303121793 0.006497318303121793 +1 FSTL1,SFRP4,HES1,TGFB2,CRB2,MSX1,CERS1,RGMA,SMAD1,SOX9 GO:0003161 cardiac conduction system development 0.007350483393547573 0.007350483393547573 +1 IRX3,GJA1,HEY1,MSX1,SMAD1 GO:0090660 cerebrospinal fluid circulation 0.008391374874553796 0.008391374874553796 +1 CCDC39,LRRC6,SPAG16 GO:0061626 pharyngeal arch artery morphogenesis 0.012342103125106045 0.012342103125106045 +1 FOLR1,HES1,TGFB2 GO:0034635 glutathione transport 0.012342103125106045 0.012342103125106045 +1 GJA1,MGST1,SLC7A11 GO:0042939 tripeptide transport 0.012342103125106045 0.012342103125106045 +1 GJA1,MGST1,SLC7A11 GO:0048568 embryonic organ development 0.013593800906162213 0.013593800906162213 +1 CCDC39,ID3,TMIE,PIFO,FOLR1,EFEMP1,PLCD3,HEY1,PAX6,HES1,TGFB2,CRB2,NDRG4,MSX1,PRRX1,SOX9 GO:0030509 BMP signaling pathway 0.015781176706907554 0.015781176706907554 +1 FSTL1,SFRP4,HES1,TGFB2,CRB2,MSX1,CERS1,RGMA,SMAD1 GO:0003007 heart morphogenesis 0.02878453489623772 0.02878453489623772 +1 CCDC39,DNAH11,FOLR1,ELN,HEY1,HES1,TGFB2,NDRG4,MSX1,CPE,SOX9 GO:0030856 regulation of epithelial cell differentiation 0.03266659334865707 0.03266659334865707 +1 FOXJ1,S1PR3,ID1,SFRP4,PAX6,HES1,CD24,SOX9 GO:0030510 regulation of BMP signaling pathway 0.03355666129581694 0.03355666129581694 +1 FSTL1,SFRP4,HES1,CRB2,MSX1,RGMA,SMAD1 GO:0030858 positive regulation of epithelial cell differentiation 0.03355666129581694 0.03355666129581694 +1 FOXJ1,SFRP4,PAX6,CD24,SOX9 GO:0048515 spermatid differentiation 0.03355666129581694 0.03355666129581694 +1 ROPN1L,RSPH1,PACRG,NME5,MNS1,IQCG,NPHP1,SPAG16 GO:0072337 modified amino acid transport 0.03804560235170004 0.03804560235170004 +1 FOLR1,GJA1,MGST1,SLC7A11 GO:0090092 regulation of transmembrane receptor protein serine/threonine kinase signaling pathway 0.04261262884602752 0.04261262884602752 +1 FOLR1,VEPH1,FSTL1,SFRP4,HES1,TGFB2,CRB2,MSX1,CERS1,RGMA,SMAD1 GO:0042692 muscle cell differentiation 0.04427330679507467 0.04427330679507467 +1 IRX3,PI16,NEK5,HEY1,CTNNA2,AGT,DNER,HES1,CSRP2,MSX1,EDNRB,SMAD1,SOX9 GO:0055017 cardiac muscle tissue growth 0.04427330679507467 0.04427330679507467 +1 PI16,GJA1,AGT,TGFB2,NDRG4,SMAD1 GO:0006857 oligopeptide transport 0.044363866249402265 0.044363866249402265 +1 GJA1,MGST1,SLC7A11 GO:0003203 endocardial cushion morphogenesis 0.0499295661834699 0.0499295661834699 +1 HEY1,TGFB2,MSX1,SOX9 WP:WP4803 Ciliopathies 2.9350465797552176e-9 2.9350465797552176e-9 +1 RSPH1,CCDC65,RSPH4A,CFAP52,ZMYND10,DNAH11,DRC1,CFAP53,DNAH6,LRRC6,TMEM231,SPAG1,EFHC1,TMEM67,NPHP1,DNAAF4,TCTEX1D2,CFAP298,TCTN1