GO.ID Description p.Val FDR Phenotype Genes GO:0036293 response to decreased oxygen levels 9.512838277589985e-9 9.512838277589985e-9 +1 HILPDA,CA9,ANGPTL4,CAV1,EPAS1,NDRG1,PLOD2,ADM,STC2,SLC2A1,EGLN3,AK4,BNIP3,NOL3,ERO1A,LOXL2,BNIP3L,FAM162A,MT3,CCN2,LDHA,PGK1,ENO1,PAM,CYBA,SEM1,CHCHD2 GO:0001666 response to hypoxia 1.5526807958182244e-8 1.5526807958182244e-8 +1 HILPDA,CA9,ANGPTL4,CAV1,EPAS1,NDRG1,PLOD2,ADM,STC2,SLC2A1,EGLN3,AK4,BNIP3,NOL3,ERO1A,LOXL2,BNIP3L,FAM162A,MT3,LDHA,PGK1,ENO1,PAM,CYBA,SEM1,CHCHD2 GO:0070482 response to oxygen levels 2.8613007852408283e-8 2.8613007852408283e-8 +1 HILPDA,CA9,ANGPTL4,CAV1,EPAS1,NDRG1,PLOD2,ADM,STC2,SLC2A1,EGLN3,AK4,BNIP3,NOL3,ERO1A,LOXL2,BNIP3L,FAM162A,MT3,CCN2,LDHA,PGK1,ENO1,PAM,CYBA,SEM1,CHCHD2 GO:0061718 glucose catabolic process to pyruvate 3.4706548569630426e-7 3.4706548569630426e-7 +1 ENO2,PFKP,GAPDH,TPI1,PGK1,GPI,ENO1,PKM GO:0006735 NADH regeneration 3.4706548569630426e-7 3.4706548569630426e-7 +1 ENO2,PFKP,GAPDH,TPI1,PGK1,GPI,ENO1,PKM GO:0061621 canonical glycolysis 3.4706548569630426e-7 3.4706548569630426e-7 +1 ENO2,PFKP,GAPDH,TPI1,PGK1,GPI,ENO1,PKM GO:0061620 glycolytic process through glucose-6-phosphate 6.333795070307992e-7 6.333795070307992e-7 +1 ENO2,PFKP,GAPDH,TPI1,PGK1,GPI,ENO1,PKM GO:0030198 extracellular matrix organization 6.671268983201467e-7 6.671268983201467e-7 +1 LOX,CAV1,PLOD2,CCN1,ERO1A,LOXL2,CD44,FN1,CAV2,NR2E1,CCN2,SERPINE1,BGN,CD151,COL6A2,FLRT2,TIMP1,AEBP1,COL4A2,GFAP,BSG,PRDX4,SPP1,ANXA2 GO:0043062 extracellular structure organization 6.671268983201467e-7 6.671268983201467e-7 +1 LOX,CAV1,PLOD2,CCN1,ERO1A,LOXL2,CD44,FN1,CAV2,NR2E1,CCN2,SERPINE1,BGN,CD151,COL6A2,FLRT2,TIMP1,AEBP1,COL4A2,GFAP,BSG,PRDX4,SPP1,ANXA2 GO:0045229 external encapsulating structure organization 6.671268983201467e-7 6.671268983201467e-7 +1 LOX,CAV1,PLOD2,CCN1,ERO1A,LOXL2,CD44,FN1,CAV2,NR2E1,CCN2,SERPINE1,BGN,CD151,COL6A2,FLRT2,TIMP1,AEBP1,COL4A2,GFAP,BSG,PRDX4,SPP1,ANXA2 GO:0061615 glycolytic process through fructose-6-phosphate 7.52160169756694e-7 7.52160169756694e-7 +1 ENO2,PFKP,GAPDH,TPI1,PGK1,GPI,ENO1,PKM GO:0071456 cellular response to hypoxia 0.0000012173072206319502 0.0000012173072206319502 +1 HILPDA,CA9,EPAS1,NDRG1,STC2,EGLN3,AK4,BNIP3,NOL3,ERO1A,BNIP3L,FAM162A,MT3,PGK1,ENO1,SEM1,CHCHD2 GO:0071453 cellular response to oxygen levels 0.0000013025279804013101 0.0000013025279804013101 +1 HILPDA,CA9,CAV1,EPAS1,NDRG1,STC2,EGLN3,AK4,BNIP3,NOL3,ERO1A,BNIP3L,FAM162A,MT3,PGK1,ENO1,SEM1,CHCHD2 GO:0006007 glucose catabolic process 0.0000019414992745358365 0.0000019414992745358365 +1 ENO2,PFKP,GAPDH,TPI1,PGK1,GPI,ENO1,PKM GO:0036294 cellular response to decreased oxygen levels 0.00000209235410153846 0.00000209235410153846 +1 HILPDA,CA9,EPAS1,NDRG1,STC2,EGLN3,AK4,BNIP3,NOL3,ERO1A,BNIP3L,FAM162A,MT3,PGK1,ENO1,SEM1,CHCHD2 GO:0001525 angiogenesis 0.0000023727629734328743 0.0000023727629734328743 +1 ANGPTL4,CAV1,EPAS1,ADM,APLN,CCN1,CHI3L1,CALD1,LOXL2,FN1,NR2E1,CCN2,PGK1,FLNA,SERPINE1,SCG2,ACTG1,PKM,TNFRSF12A,CCN3,COL4A2,BSG,EFNA3,ANXA2,TYMP,ANXA1 GO:0019674 NAD metabolic process 0.0000025833599943837407 0.0000025833599943837407 +1 ENO2,PFKP,GAPDH,TPI1,LDHA,PGK1,GPI,ENO1,PKM GO:2000147 positive regulation of cell motility 0.000006518133642974352 0.000006518133642974352 +1 AKAP12,CAV1,IGFBP5,FGFR1,RARRES2,CCN1,LGALS3,FN1,EGFR,FLNA,GPI,CD74,SERPINE1,MET,CAVIN1,ACTG1,RACK1,EDN2,AIF1,CD151,FAM110C,CD99,PHPT1,TCAF2,BSG,ANXA1 GO:0006734 NADH metabolic process 0.000012170953532674769 0.000012170953532674769 +1 ENO2,PFKP,GAPDH,TPI1,PGK1,GPI,ENO1,PKM GO:0052547 regulation of peptidase activity 0.00001920020921382687 0.00001920020921382687 +1 CAV1,EGLN3,NOL3,PCOLCE2,CCN1,PERP,GAPDH,CD44,FN1,FAM162A,MT3,CCN2,GPI,SERPINE1,LAPTM5,RACK1,LAMTOR5,TIMP1,PDCD5,EFNA3,ANXA2 GO:0030335 positive regulation of cell migration 0.00003678943716242366 0.00003678943716242366 +1 AKAP12,CAV1,IGFBP5,FGFR1,RARRES2,CCN1,LGALS3,FN1,EGFR,FLNA,GPI,CD74,SERPINE1,MET,ACTG1,RACK1,EDN2,AIF1,CD151,FAM110C,CD99,TCAF2,BSG,ANXA1 GO:0019320 hexose catabolic process 0.000052325700693765276 0.000052325700693765276 +1 ENO2,PFKP,GAPDH,TPI1,PGK1,GPI,ENO1,PKM GO:0046365 monosaccharide catabolic process 0.00010170835982715437 0.00010170835982715437 +1 ENO2,PFKP,GAPDH,TPI1,PGK1,GPI,ENO1,PKM GO:0046031 ADP metabolic process 0.0001141468214018429 0.0001141468214018429 +1 ENO2,AK4,PFKP,GAPDH,TPI1,LDHA,PGK1,PFKFB4,GPI,ENO1,PKM GO:0031099 regeneration 0.00019949062190838693 0.00019949062190838693 +1 ADM,EGFR,MTPN,FLNA,GAP43,MAP1B,CCN3,PTPRF,GFAP,SPP1,RPS15,ANXA1,NACA GO:0006165 nucleoside diphosphate phosphorylation 0.0002168207981957544 0.0002168207981957544 +1 ENO2,AK4,PFKP,GAPDH,TPI1,LDHA,PGK1,PFKFB4,GPI,ENO1,PKM GO:0001819 positive regulation of cytokine production 0.00022213869543700175 0.00022213869543700175 +1 HILPDA,AKAP12,TSLP,CHI3L1,GAPDH,CLU,CD74,SERPINE1,TYROBP,LAPTM5,HLA-DPA1,FCER1G,CYBA,LAMTOR5,HLA-DPB1,AIF1,B2M,STMP1,BSG,CEBPG,ANXA1 GO:0043687 post-translational protein modification 0.00022213869543700175 0.00022213869543700175 +1 IGFBP3,EPAS1,IGFBP5,STC2,CCN1,FN1,OBSL1,FBXO17,FSTL3,PRSS23,SCG2,SEM1,TIMP1,CALU,SPP1,FAM20C,IGFBP7,RCN1 GO:0046939 nucleotide phosphorylation 0.00023458076791118312 0.00023458076791118312 +1 ENO2,AK4,PFKP,GAPDH,TPI1,LDHA,PGK1,PFKFB4,GPI,ENO1,PKM GO:0052548 regulation of endopeptidase activity 0.0002448308236415785 0.0002448308236415785 +1 EGLN3,NOL3,CCN1,PERP,GAPDH,CD44,FAM162A,MT3,CCN2,GPI,SERPINE1,LAPTM5,RACK1,LAMTOR5,TIMP1,PDCD5,EFNA3,ANXA2 GO:0009135 purine nucleoside diphosphate metabolic process 0.00026238297719304336 0.00026238297719304336 +1 ENO2,AK4,PFKP,GAPDH,TPI1,LDHA,PGK1,PFKFB4,GPI,ENO1,PKM GO:0009179 purine ribonucleoside diphosphate metabolic process 0.00026238297719304336 0.00026238297719304336 +1 ENO2,AK4,PFKP,GAPDH,TPI1,LDHA,PGK1,PFKFB4,GPI,ENO1,PKM GO:0006096 glycolytic process 0.00030106202113325996 0.00030106202113325996 +1 ENO2,PFKP,GAPDH,TPI1,LDHA,PGK1,PFKFB4,GPI,ENO1,PKM GO:0001765 membrane raft assembly 0.00030375818904953937 0.00030375818904953937 +1 CAV1,S100A10,CAV2,ANXA2 GO:0009185 ribonucleoside diphosphate metabolic process 0.00031214247698774635 0.00031214247698774635 +1 ENO2,AK4,PFKP,GAPDH,TPI1,LDHA,PGK1,PFKFB4,GPI,ENO1,PKM GO:0006757 ATP generation from ADP 0.00031709660705207744 0.00031709660705207744 +1 ENO2,PFKP,GAPDH,TPI1,LDHA,PGK1,PFKFB4,GPI,ENO1,PKM GO:0097529 myeloid leukocyte migration 0.00031709660705207744 0.00031709660705207744 +1 PRTN3,RARRES2,LGALS3,CD74,SERPINE1,SCG2,FCER1G,EDN2,AIF1,CCN3,CD99,BSG,ANXA1 GO:0045047 protein targeting to ER 0.00039177539640007696 0.00039177539640007696 +1 SEC61G,RPL36,RPS28,RPS4Y1,RPL24,RPLP0,RPL35A,RPL32,RPS15,RPS5 GO:0006091 generation of precursor metabolites and energy 0.0004342874129236784 0.0004342874129236784 +1 ENO2,AK4,BNIP3,PFKP,GAPDH,LOXL2,TPI1,MT3,LDHA,COX7A1,PGK1,PFKFB4,GBE1,NDUFA4L2,GPI,NDUFA5,ENO1,PKM,CYBA,CHCHD2,IMMP2L,PPP1R3C GO:0061448 connective tissue development 0.0004672223995993887 0.0004672223995993887 +1 LOX,FRZB,CHRDL2,CCN1,CHI3L1,LOXL2,CD44,CCN2,BGN,SLC39A14,PKD1,CCN3,ARRDC3,TIMP1 GO:0006605 protein targeting 0.00047392058662393467 0.00047392058662393467 +1 BNIP3L,SEC61G,CLU,RPL36,LAPTM5,RPS28,RPS4Y1,MTCL1,RPL24,RPLP0,TOMM7,RPL35A,RPL32,TCAF2,PDCD5,IMMP2L,RPS15,RPS5,NACA GO:0006090 pyruvate metabolic process 0.00048398776359463675 0.00048398776359463675 +1 ENO2,PFKP,GAPDH,TPI1,LDHA,PGK1,PFKFB4,GPI,ENO1,PKM,BSG GO:0072599 establishment of protein localization to endoplasmic reticulum 0.000492163899193335 0.000492163899193335 +1 SEC61G,RPL36,RPS28,RPS4Y1,RPL24,RPLP0,RPL35A,RPL32,RPS15,RPS5 GO:0060326 cell chemotaxis 0.0005930493717274004 0.0005930493717274004 +1 LOX,FGFR1,RARRES2,LGALS3,CD74,SERPINE1,SCG2,MET,FCER1G,EDN2,AIF1,CCN3,SBDS,BSG,ANXA1 GO:0051216 cartilage development 0.0005930493717274004 0.0005930493717274004 +1 FRZB,CHRDL2,CCN1,CHI3L1,LOXL2,CD44,CCN2,BGN,SLC39A14,PKD1,CCN3,TIMP1 GO:0070972 protein localization to endoplasmic reticulum 0.0006017260212022654 0.0006017260212022654 +1 INSIG2,SEC61G,RPL36,RPS28,RPS4Y1,RPL24,RPLP0,RPL35A,RPL32,RPS15,RPS5 GO:0010038 response to metal ion 0.000628869172330342 0.000628869172330342 +1 CAV1,NDRG1,IGFBP2,BNIP3,LOXL2,MT3,FSTL3,EGFR,MAP1LC3A,GPI,C1QA,PAM,SNCB,B2M,S100A16,BSG,MT1X GO:0048678 response to axon injury 0.0006389329188042779 0.0006389329188042779 +1 BNIP3,FLNA,TYROBP,GAP43,MAP1B,AIF1,PTPRF,SPP1 GO:0006614 SRP-dependent cotranslational protein targeting to membrane 0.0006709930566968927 0.0006709930566968927 +1 RPL36,RPS28,RPS4Y1,RPL24,RPLP0,RPL35A,RPL32,RPS15,RPS5 GO:0031102 neuron projection regeneration 0.0006897495386983197 0.0006897495386983197 +1 ADM,FLNA,GAP43,MAP1B,PTPRF,GFAP,SPP1